Essential Questions:
  • What is a Karyotype?
A Karyotype is a profile of one's chromosomes. In a Karyotype, there are 23 pairs which are numbered by size, with #1 being the largest two chromosomes.
  • How is a Karyotype made and interpreted?
A karyotype is made by taking a picture of someone's chromosomes during anaphase, cutting them out and matching them up using size, banding pattern and centromere position as guides. A karyotype is interpreted by seeing if the number of chromosomes is n and not n+1, n-1 etc.
  • What kinds of errors can happen during Meiosis and what are examples of disorders caused by these errors?
Nondisjunction errors can happen during Meiosis i.e the chromosomes do not split properly during Anaphase. Down Syndrome, Turners Syndrome and Klinefelter's are some of the disorders caused by these errors.


Procedure:
Visit the Genetics Learning Center site from the University of Utah Karyotyping page. Complete the interactive on the first page (you can even try it yourself). Move on the next page, read and complete each interactive animation. If you like, you can also complete the self-quiz at the end.